The aim of this research was to compare the tissue response in treated defects with bone matrix with bovine or human origin. Was realized a descriptive study with 12 rabbits where was executed two defects in the skull in relation to conventional techniques. Randomized defects were used to put bone matrix with bovine or human origin; histological exam was realized in the week number 7 and 15 with 6 animals each. At 7 weeks was observed a limited inflammatory infiltrate with clear differences between the peripheral bone and the filled bone and in the 15 weeks of analysis was observed the presence of some particulate of the bone graft beside a new bone into the defect; was not observed any differences in the sequence of repair or delayed in the bovine or human material. It´s concluded that both materials are useful in bone regeneration for this experimental model.

El objetivo de esta investigación fue comparar la respuesta tisular en defectos tratados con matriz óseo de origen bovino y humano. Se realizó un estudio descriptivo con 12 conejos en los cuales se confeccionaron dos defectos en la calota craneana de acuerdo a procesos convencionales. Cada defecto fue aleatoriamente rellenado con matriz ósea bovina o con matriz ósea humana; se realizaron evaluaciones histológicas a las 7 y 15 semanas de realizada la cirugía (6 animales en cada grupo). A las 7 semanas se identificó un leve infiltrado inflamatorio y claras diferencias entre el hueso periférico y el sitio injertado, mientras que a las 15 semanas se observo la persistencia de algunas partículas injertadas y la presencia de hueso nuevo formado en el defecto; no se logró identificar diferencias en la secuencia de reparación o retrasos en la misma con ninguno de los dos materiales. Se concluye que ambos materiales son útiles en la regeneración ósea en el presente modelo experimental.

Electrical stimulation has been used in different conditions for tissue regeneration. The aim of this study was to analyze the tissue response of defects created in rabbit skulls to electrical stimulation. Two groups were formed, each with 9 New Zealand rabbits; two 5 mm defects were made, one in each parietal, with one being randomly filled with autogenous bone extracted as particles and the other maintained only with blood clotting. The rabbits were euthanized at 8 weeks and 15 weeks to then study the samples collected histologically. In the 8-week analysis bone formation was observed in the defects in the test and control filled with bone graft, whereas the defects with clotting presented a very early stage of bone formation with abundant connective tissue. At 15 weeks an advanced stage of bone regeneration was identified in the defects with bone graft, whereas no significant differences were found in the electrically stimulated defects. In conclusion, electrical stimulus does not alter the sequence of bone formation; new studies could help establish patterns and influences of the stimulus on bone regeneration.

La estimulación eléctrica ha sido empleada en diferentes condiciones para la regeneración de tejidos. El objetivo de esta investigación es analizar la respuesta tisular de defectos creados en cráneo de conejos a la estimulación eléctrica. Se formaron 2 grupos con 9 conejos de raza New Zealand cada uno; en ellos se realizaron dos defectos de 5 mm, uno en cada parietal, siendo aleatoriamente uno rellenado con el propio hueso autógeno extraído en forma de partículas y el otro mantenido solo con coagulo sanguíneo; se realizó la eutanasia a las 8 semanas y a las 15 semanas para luego estudiar histológicamente las muestras recolectadas. En el análisis de 8 semanas se observó formación ósea en los defectos test y control rellenados con injerto óseo mientras que los defectos con coagulo presentaron un estado muy precoz de formación ósea, observándose abundante tejido conectivo. A las 15 semanas se identificó un estado avanzado de regeneración ósea en los defectos con injerto óseo, donde no se apreció diferencias importantes en los defectos estimulados eléctricamente. Se concluye que el estimulo eléctrico no altera la secuencia de formación ósea; nuevos estudios podrían contribuir a establecer patrones e influencias del estimulo eléctrico en la regeneración ósea.

An Integral equation formulation for steady flow of a viscous fluid is presented based on the boundary element method. The continuity, Navier-Stokes and energy equations are used for calculation of the flow field. The governing differential equations, in terms of primitive variables, are derived using velocity-pressure-temperature. The calculation of fundamental solutions and solutions tensor is showed. Applications to simple flow cases, such as the driven cavity, step, deep cavity and channel of multiple obstacles are presented. Convergence difficulties are indicated, which have limited the applications to flows of low Reynolds numbers.

A sismicidade do SE do Brasil foi estudada com a operação adicional de estações digitais e analógicas temporárias. Estações locais e regionais permitiram a determinação de três novos mecanismos focais compostos para as séries de sismos de Betim 1992/93, Formiga 1993, e para os sismos induzidos pelo reservatório de Nova Ponte em 1995, todos em Minas Gerais. Os mecanismos focais na parte sul do cráton do São Francisco e na faixa de dobramentos Brasília indicam falhamentos inversos e normais, com uma direção comum para a tensão horizontal máxima entre E-W e NE-SW. Longe da margem continental, os mecanismos focais são consistentes com a direção teórica dos esforços determinada com modelamento por elementos finitos das forças tectônicas que atuam na placa sul-americana. Perto da Serra do Mar, o padrão de esforços parece mais complexo. Uma seleção do catálogo de sismos do Brasil, usando limites de detectabilidade diferentes para cada época para se obter uma cobertura geográficamente uniforme, revelou duas áreas sísmicas principais: 1) a plataforma continental, e 2) a parte sul da Faixa Brasília e Cráton do São Francisco. A área montanhosa das Serras do Mar e da Mantiqueira (na Faixa Ribeira), e a Bacia do Paraná são muito menos ativas sismicamente.

The seismicity of SE Brazil is studied with a recent deployment of additional temporary digital and analog seismographic stations. Regional and local stations have allowed the determination of three new composite focal mechanisms for the earthquake series of Betim in 1992/93, Formiga in 1993, and the reservoir-induced events of Nova Ponte in 1995, all in Minas Gerais state. The focal mechanism data in the southern part of the São Francisco craton and adjacent Brasília fold belt indicate both normal and reverse faulting with a common E-W to NE-SW orientation of the maximum horizontal stress. Far from the continental margin, the focal mechanisms are consistent with theoretical estimates of stress directions from finite-element modelings of the forces driving the South American plate. Near the Serra do Mar coastal range, the stress pattern seems more complex. A selection of the earthquake catalog, using threshold magnitudes varying in time to yield a data set with spatially uniform coverage, indicates two main seismic areas: 1) the offshore continental shelf , and 2) the southern part of the Brasília fold belt and the São Francisco craton. The high topography areas of the Serra do Mar and Serra da Mantiqueira (in the Ribeira fold belt) and the Paraná basin are much less seismically active.